SOCIETAL CHALLENGES Lectures 2023
To feed or not to feed – How tumor cells adapt to their nutrient environment
09 February 2023, 14:00-15:30 CET
Limited supply and catabolism restrict nutrient access in tumors. Tumors have, therefore, to cope with limitations in essential amino acids while sustaining protein biosynthesis. In my talk we will dive into cancer signaling and metabolism, and we will cover the nutrient challenges in tumors. I will present recent discoveries of unexpected mechanisms enabling tumors to sustain anabolic processes and growth under nutrient stress. We will discuss the tumor vulnerabilities and new avenues for therapies arising from our findings.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 754688 (https://mesi-strat.eu/).
Visit www.metabolic-signaling.eu or more information on our projects.
Kathrin Thedieck is Full Professor and Institute Head for Biochemistry at the University of Innsbruck since 2019. She studied in Münster, Strasbourg and Hannover before she completed her PhD at the Div. of Cell and Immune Biology (Prof. J. Wehland) at the Hemholtz Centre for Infection Research (HZI) and the TU Braunschweig. As Postdoc she was working at the Dept. of Biochemistry (Prof. Michael N. Hall) at University of Basel and Group Leader Functional Proteomics of Metabolic Signaling at the University of Freiburg. In 2013 she became Adjunct Professor at the European Medical School Oldenburg – Groningen, driven by the Universities of Groningen (NL) and Oldenburg. She received several awards and since 2022 she holds an ERC Advanced Grant.